Human Skin Model for Anti-Aging Test Service

The cosmetic industry has a long history and technological advancements have made them available to the masses. 3D human skin models have become the latest tool for non-animal testing in the skincare and cosmetic market. The human skin model from Creative Biolabs is a laboratory-grown skin test platform to discover the potential effects of skincare products, cosmetics, health products, etc. on human skin. Our comprehensive capabilities allow for a full range of testing.

Human Skin Model for Anti-Aging Test

In humans, skin aging is a complex biological process that involves multiple intrinsic and extrinsic factors. The three structural components of the dermis, including collagen, elastin, and glycosaminoglycans, have been the focus of most anti-aging research efforts. In particular, decreased collagen levels weaken the bond between the dermis and epidermis leading to changes in skin structure and the formation of wrinkles.

Treatment of our human skin models with anti-aging compounds made it possible to observe whether fibroblasts in the extracellular matrix produced more collagen than untreated fibroblasts. Thereby verifying the anti-aging efficacy of the compound. In addition, inflammatory processes can also significantly accelerate skin aging, so our skin model can also be used to test novel compounds with anti-inflammatory properties. In this process, it is first necessary to induce inflammation in the skin model with an irritant, and then treat it with an anti-inflammatory substance and observe whether the epidermal swelling is reduced. Using our human skin models, cosmetic products can be tested for their anti-aging effects.

Factors Related to Intrinsic Aging

Ethnicity: The effect of ethnicity on aging is mainly reflected in differences in pigmentation.
Anatomic variations: Certain areas of the skin are thinner and therefore aging becomes more pronounced.
Hormonal changes: Estrogen affects the synthesis of collagen by fibroblasts and thus affects aging.

Advantages of our Test Service

Comply with all applicable regulations and ethics.
As an alternative to animal testing.
Better predictability due to the use of live human skin.
More human-specific.
Customized services to meet your special project needs.

Equipped with world-leading technology platforms and professional scientific staff, we are pleased to offer the most qualified services and products for our customers all over the world. If you are interested in our products or services, please do not hesitate to contact us for more detailed information.